It helps regulate blood pressure by controlling levels of the protein angiotensin, which encourages blood vessels to constrict and raise blood pressure. The ACE-2 receptor is embedded in cellular membranes. Studies show that SARS-CoV-2 enters intestinal cells and respiratory cells using the angiotensin-converting enzyme 2 (ACE-2) protein as a receptor. There is evidence that SARS-CoV-2 can infect cells in the respiratory and GI tract, as well as cells in other areas. Researchers are still learning how infection with SARS-CoV-2 affects different parts of the body. Abdominal pain is less common, occurring in less than 10%.” Approximately 40% of patients with COVID-19 will have loss of appetite, and up to 50% will have diarrhea. Nausea and vomiting may be present in up to two-thirds of patients with COVID-19. “ symptoms are common, with up to one-third of patients with COVID-19 presenting first with GI symptoms. And, according to a clinical update that appeared in The American Journal of Emergency Medicine in January 2022: And sometimes, these symptoms developed before respiratory symptoms or a fever.Įarly studies suggest that GI symptoms tend to occur in the early stages of the infection. However, a review from late 2020 reported that 16% of people with SARS-CoV-2 infections only experienced GI symptoms. It seems that most people with GI symptoms of COVID-19 develop them alongside respiratory symptoms. The disease may also destroy bowel tissues and reduce intestinal movement. Less commonly, COVID-19 may also be associated with:
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